Het aantal gebruikers van astma- en COPD-middelen, 2003 - 2021
| 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ATC-code | |||||||||||||||||||
| R03AC02 Salbutamol | 643.927 | 652.982 | 663.889 | 685.911 | 723.194 | 726.714 | 762.262 | 763.155 | 787.932 | 781.921 | 762.393 | 781.813 | 811.866 | 833.424 | 823.275 | 856.716 | 865.514 | 799.221 | 768.693 |
| R03AC03 Terbutaline | 77.215 | 65.030 | 60.077 | 57.016 | 54.044 | 46.360 | 44.528 | 40.203 | 37.761 | 34.188 | 32.001 | 31.218 | 30.274 | 29.172 | 27.407 | 26.408 | 25.147 | 23.569 | 20.133 |
| R03AC12 Salmeterol | 86.074 | 73.727 | 63.381 | 54.767 | 48.978 | 46.048 | 43.808 | 41.768 | 40.024 | 38.347 | 36.700 | 35.573 | 35.539 | 35.969 | 35.356 | 34.345 | 33.572 | 30.444 | 27.233 |
| R03AC13 Formoterol | 89.831 | 81.472 | 75.070 | 69.374 | 66.350 | 65.430 | 63.358 | 61.830 | 60.009 | 59.295 | 57.720 | 56.258 | 55.475 | 54.493 | 52.683 | 51.439 | 49.779 | 47.206 | 47.368 |
| R03AC18 Indacaterol | . | . | . | . | . | . | . | 3.593 | 11.304 | 14.424 | 16.170 | 14.351 | 11.677 | 9.144 | 7.421 | 6.166 | 5.023 | 3.932 | 3.359 |
| R03AC19 Olodaterol | . | . | . | . | . | . | . | . | . | . | . | 1.645 | 4.141 | 3.610 | 3.057 | 2.827 | 2.634 | 2.317 | 2.181 |
| R03AK06 Salmeterol met fluticason | 233.146 | 283.574 | 325.293 | 356.634 | 370.418 | 372.101 | 375.920 | 378.317 | 372.959 | 362.669 | 342.094 | 319.427 | 299.064 | 274.508 | 252.692 | 234.018 | 214.958 | 197.635 | 160.105 |
| R03AK07 Formoterol met budesonide | 101.141 | 137.643 | 169.152 | 191.037 | 220.625 | 225.740 | 233.931 | 243.033 | 243.232 | 233.430 | 215.921 | 202.290 | 194.425 | 183.249 | 173.665 | 166.423 | 161.180 | 156.006 | 149.506 |
| R03AK08 Formoterol met beclometason | . | . | . | . | 55 | 7.707 | 19.677 | 33.965 | 49.975 | 67.349 | 87.183 | 109.872 | 130.740 | 148.030 | 166.526 | 182.720 | 200.854 | 214.010 | 235.575 |
| R03AK10 Vilanterol met fluticasonfuroaat | . | . | . | . | . | . | . | . | . | . | . | 2.618 | 7.959 | 11.439 | 15.419 | 18.996 | 20.328 | 22.595 | 39.969 |
| R03AK11 Formoterol met fluticason | . | . | . | . | . | . | . | . | . | 758 | 4.482 | 6.086 | 7.337 | 8.167 | 8.086 | 7.841 | 7.756 | 7.736 | 7.649 |
| R03AK12 Salmeterol met budesonide | . | . | . | . | . | . | . | . | . | . | . | . | . | 13 | 36 | 64 | 79 | 86 | 108 |
| R03AK14 Indacaterol met mometason | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 94 |
| R03AL01 Fenoterol met ipratropiumbromide | 37.587 | 31.316 | 27.112 | 23.983 | 21.230 | 33.438 | 31.115 | 28.725 | 26.914 | 24.154 | 22.059 | 20.906 | 21.349 | 21.322 | 22.015 | 23.467 | 24.120 | 24.986 | 27.105 |
| R03AL02 Salbutamol met ipratropiumbromide | 32.692 | 36.518 | 41.096 | 39.988 | 44.734 | 30.718 | 14.982 | 16.047 | 16.682 | 17.139 | 17.276 | 17.442 | 18.372 | 19.165 | 20.467 | 21.705 | 22.761 | 17.723 | 15.955 |
| R03AL03 Vilanterol met umeclidiniumbromide | . | . | . | . | . | . | . | . | . | . | . | 90 | 3.135 | 4.636 | 5.893 | 7.428 | 8.029 | 7.434 | 8.284 |
| R03AL04 Indacaterol met glycopyrroniumbromide | . | . | . | . | . | . | . | . | . | . | 1.068 | 8.626 | 12.172 | 12.601 | 13.425 | 13.068 | 12.111 | 10.322 | 9.245 |
| R03AL05 Formoterol met aclidiniumbromide | . | . | . | . | . | . | . | . | . | . | . | . | 2.371 | 4.334 | 4.940 | 5.184 | 5.023 | 4.338 | 4.332 |
| R03AL06 Olodaterol met tiotropiumbromide | . | . | . | . | . | . | . | . | . | . | . | . | 3.325 | 14.823 | 23.008 | 29.411 | 34.698 | 35.186 | 36.916 |
| R03AL07 Formoterol met glycopyrroniumbromide | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 1.240 | 4.139 |
| R03AL08 Vilanterol met umeclidiniumbromide en fluticasonfuroaat | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 3.121 | 5.427 | 5.637 | 7.201 |
| R03AL09 Formoterol met glycopyrroniumbromide en beclometason | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 254 | 8.524 | 21.457 | 28.189 | 37.875 |
| R03AL11 Formoterol met glycopyrroniumbromide en budesonide | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 460 |
| R03AL12 Indacaterol met glycopyrroniumbromide en mometason | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 10 | 227 |
| R03BA01 Beclometason | 147.509 | 102.637 | 94.193 | 89.739 | 84.613 | 81.852 | 83.886 | 85.195 | 86.993 | 85.030 | 79.204 | 77.292 | 76.792 | 74.492 | 73.340 | 71.098 | 69.005 | 64.769 | 62.041 |
| R03BA02 Budesonide | 187.713 | 161.273 | 139.044 | 132.174 | 122.022 | 107.356 | 98.733 | 89.760 | 83.019 | 75.330 | 67.845 | 64.595 | 63.312 | 60.464 | 58.501 | 60.815 | 62.451 | 58.516 | 57.200 |
| R03BA05 Fluticason | 307.484 | 306.764 | 295.036 | 301.878 | 294.249 | 275.751 | 275.433 | 262.596 | 255.446 | 241.009 | 221.642 | 215.172 | 210.626 | 200.938 | 192.404 | 180.816 | 172.638 | 157.665 | 143.139 |
| R03BA08 Ciclesonide | . | . | 1.418 | 8.797 | 17.653 | 27.486 | 34.218 | 40.469 | 47.572 | 53.072 | 56.079 | 59.203 | 62.640 | 65.416 | 68.305 | 69.976 | 70.221 | 68.242 | 65.374 |
| R03BB01 Ipratropium | 195.723 | 165.099 | 148.783 | 124.805 | 116.510 | 118.430 | 110.689 | 107.374 | 103.756 | 101.831 | 98.986 | 97.169 | 99.775 | 97.070 | 98.514 | 99.087 | 96.979 | 87.006 | 77.312 |
| R03BB04 Tiotropium | 105.148 | 134.532 | 156.396 | 165.817 | 180.962 | 202.756 | 210.836 | 226.884 | 238.025 | 245.215 | 244.215 | 238.957 | 239.242 | 228.312 | 220.488 | 209.833 | 195.199 | 176.023 | 157.139 |
| R03BB05 Aclidiniumbromide | . | . | . | . | . | . | . | . | . | . | 2.715 | 5.824 | 6.837 | 6.620 | 6.169 | 5.672 | 5.112 | 4.336 | 4.237 |
| R03BB06 Glycopyrroniumbromide | . | . | . | . | . | . | . | . | . | . | 11.582 | 12.154 | 11.397 | 9.921 | 8.921 | 7.847 | 6.870 | 5.611 | 5.060 |
| R03BB07 Umeclidiniumbromide | . | . | . | . | . | . | . | . | . | . | . | . | 299 | 1.188 | 2.698 | 3.466 | 3.481 | 4.549 | 10.365 |
| R03BC01 Cromoglicinezuur | 6.701 | 5.682 | 4.413 | 4.217 | 3.598 | 2.991 | 2.594 | 2.313 | 2.070 | 1.754 | 1.575 | 1.465 | 1.290 | 1.168 | 1.084 | 1.107 | 946 | 794 | 389 |
| R03BC03 Nedocromil | 2.153 | 1.949 | 1.559 | 1.503 | 1.258 | 1.121 | 967 | 863 | 836 | 720 | 589 | 526 | 435 | 375 | 325 | 253 | 60 | 5 | . |
| R03BX Overige middelen bij astma/copd voor inhalatie | 26 | 14 | 10 | 3 | 13 | 15 | 6 | 10 | 366 | 187 | 151 | 145 | 82 | 5 | . | . | . | . | . |
| R03CC02 Salbutamol | 5.427 | 4.280 | 3.818 | 3.688 | 2.534 | 1.856 | 1.776 | 1.432 | 1.140 | 984 | 745 | 504 | 410 | 351 | 283 | 324 | 208 | 83 | 60 |
| R03DA04 Theofylline | 28.145 | 24.741 | 22.379 | 17.958 | 16.053 | 14.747 | 12.849 | 11.509 | 10.097 | 8.651 | 7.453 | 5.898 | 4.671 | 4.009 | 3.478 | 2.967 | 2.328 | 963 | 600 |
| R03DC03 Montelukast | 28.395 | 35.971 | 45.699 | 53.419 | 57.736 | 57.861 | 58.158 | 59.259 | 60.967 | 59.948 | 56.009 | 53.907 | 51.676 | 49.801 | 49.292 | 48.535 | 48.770 | 47.453 | 46.419 |
| R03DX07 Roflumilast | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 64 | 450 | 539 | 493 |
| R05CB01 Acetylcysteine | 55.012 | 42.955 | 42.768 | 39.541 | 42.475 | 41.850 | 37.429 | . | . | . | . | . | . | . | . | . | . | . | . |
| R05CB13 Deoxyribonuclease | 643 | 658 | 696 | 853 | 887 | 945 | 1.005 | 975 | 975 | 975 | 991 | 971 | 973 | 976 | 991 | 963 | 963 | 947 | 925 |
| Totaal * | 1.324.755 | 1.347.844 | 1.387.272 | 1.458.053 | 1.499.411 | 1.490.505 | 1.530.106 | 1.538.534 | 1.559.326 | 1.539.904 | 1.497.126 | 1.496.386 | 1.521.087 | 1.523.295 | 1.502.052 | 1.524.614 | 1.528.349 | 1.455.779 | 1.429.804 |