Het aantal gebruikers van diabetesmiddelen, 2003 - 2021
2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ATC-code | |||||||||||||||||||
A10AB01 Insuline (humaan) | 40.541 | 35.740 | 30.776 | 26.623 | 20.721 | 16.656 | 13.752 | 11.995 | 10.339 | 7.967 | 3.440 | 2.962 | 2.641 | 2.439 | 2.213 | 2.010 | 1.768 | 1.544 | 1.385 |
A10AB04 Insuline lispro | 17.741 | 17.827 | 17.664 | 18.438 | 17.943 | 17.780 | 17.339 | 17.244 | 17.103 | 16.758 | 16.038 | 15.731 | 16.307 | 16.132 | 16.022 | 15.475 | 14.803 | 14.138 | 14.198 |
A10AB05 Insuline aspart | 35.493 | 49.049 | 60.323 | 71.987 | 82.262 | 91.315 | 97.960 | 105.184 | 113.285 | 124.935 | 129.282 | 132.499 | 137.250 | 138.679 | 142.360 | 143.362 | 144.000 | 145.257 | 148.205 |
A10AB06 Insuline glulisine | . | . | 312 | 1.759 | 3.392 | 6.104 | 7.703 | 9.484 | 10.237 | 9.388 | 10.681 | 11.766 | 12.447 | 12.655 | 12.543 | 12.188 | 11.418 | 10.754 | 10.419 |
A10AC01 Insuline (humaan) | 89.178 | 76.479 | 58.516 | 46.666 | 41.284 | 37.290 | 33.225 | 30.840 | 28.484 | 26.718 | 26.205 | 27.766 | 28.995 | 28.661 | 28.069 | 27.167 | 27.834 | 28.196 | 29.165 |
A10AD01 Insuline (humaan) | 87.793 | 77.900 | 67.380 | 55.277 | 41.361 | 31.141 | 7.492 | 4.849 | 3.792 | 3.306 | 2.357 | 2.118 | 2.020 | 1.825 | 1.652 | 1.425 | 1.260 | 1.049 | 877 |
A10AD04 Insuline lispro | 5.300 | 4.931 | 4.379 | 3.541 | 3.243 | 3.188 | 2.932 | 2.746 | 2.553 | 2.367 | 2.223 | 2.049 | 1.898 | 1.710 | 1.623 | 1.428 | 1.279 | 1.110 | 974 |
A10AD05 Insuline aspart | 18.446 | 28.328 | 34.367 | 38.591 | 50.241 | 70.862 | 73.908 | 72.470 | 67.558 | 64.630 | 60.753 | 57.083 | 53.739 | 49.169 | 44.532 | 38.389 | 33.454 | 29.310 | 25.426 |
A10AD06 Insuline degludec met insuline aspart | . | . | . | . | . | . | . | . | . | . | . | . | . | 64 | 2.525 | 5.167 | 6.214 | 6.340 | 6.174 |
A10AE04 Insuline glargine | 13.410 | 37.190 | 50.302 | 63.958 | 71.979 | 82.199 | 88.699 | 96.523 | 102.070 | 108.631 | 115.514 | 120.556 | 127.590 | 129.713 | 129.943 | 127.052 | 125.161 | 124.110 | 125.334 |
A10AE05 Insuline detemir | . | 8.307 | 20.268 | 25.435 | 31.666 | 37.383 | 42.428 | 45.659 | 47.733 | 50.145 | 50.370 | 49.769 | 48.726 | 43.254 | 37.633 | 32.496 | 28.601 | 25.125 | 22.714 |
A10AE06 Insuline degludec | . | . | . | . | . | . | . | . | . | . | . | 232 | 4.245 | 17.870 | 29.583 | 37.801 | 43.493 | 47.159 | 49.867 |
A10AE54 Insuline glargine met lixisenatide | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 160 | 419 | 587 | 503 | 378 |
A10AE56 Insuline degludec met liraglutide | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 1.911 | 2.820 | 2.758 | 2.197 | 1.755 |
A10AF01 Insuline (humaan) | . | . | . | . | 10 | 4 | 1 | . | . | . | . | . | . | . | . | . | 6 | 17 | 16 |
A10BA02 Metformine | 293.065 | 347.376 | 384.798 | 425.584 | 455.538 | 494.789 | 521.883 | 565.535 | 586.525 | 607.675 | 619.952 | 625.291 | 637.090 | 635.425 | 648.711 | 651.908 | 654.392 | 659.801 | 668.946 |
A10BB01 Glibenclamide | 42.419 | 35.992 | 29.295 | 25.226 | 20.410 | 16.881 | 14.080 | 11.797 | 9.530 | 8.184 | 6.853 | 5.212 | 4.005 | 3.134 | 2.608 | 2.114 | 1.683 | 1.278 | 548 |
A10BB03 Tolbutamide | 92.738 | 89.645 | 85.333 | 81.161 | 77.506 | 78.314 | 79.790 | 83.996 | 86.999 | 91.027 | 89.358 | 76.321 | 65.453 | 56.017 | 48.804 | 41.831 | 35.525 | 30.353 | 26.502 |
A10BB09 Gliclazide | 76.199 | 75.398 | 72.254 | 68.979 | 65.949 | 66.026 | 62.000 | 61.920 | 60.508 | 60.252 | 74.936 | 115.499 | 147.800 | 171.811 | 195.193 | 213.945 | 231.712 | 245.138 | 264.992 |
A10BB12 Glimepiride | 113.594 | 126.304 | 130.588 | 132.063 | 131.917 | 134.972 | 130.661 | 132.027 | 129.928 | 126.889 | 119.528 | 101.846 | 86.558 | 72.627 | 62.815 | 53.930 | 46.091 | 39.219 | 33.871 |
A10BD02 Metformine met sulfonylureumderivaten | 2.968 | 3.310 | 2.820 | 2.691 | 2.238 | 1.748 | 1.425 | 1.281 | 1.098 | 921 | 566 | 480 | 425 | 376 | 321 | 254 | 227 | 183 | 238 |
A10BD05 Metformine met pioglitazon | . | . | . | . | 43 | 222 | 262 | 486 | 483 | 385 | 302 | 251 | 195 | 176 | 153 | 129 | 98 | 73 | 78 |
A10BD07 Metformine met sitagliptine | . | . | . | . | . | 439 | 1.367 | 3.068 | 4.576 | 5.942 | 6.277 | 6.014 | 5.684 | 5.457 | 5.463 | 5.550 | 5.656 | 5.602 | 5.432 |
A10BD08 Metformine met vildagliptine | . | . | . | . | . | 382 | 1.614 | 3.124 | 3.963 | 4.739 | 5.054 | 4.944 | 4.625 | 4.354 | 4.276 | 4.188 | 4.150 | 3.888 | 3.712 |
A10BD10 Metformine met saxagliptine | . | . | . | . | . | . | . | . | . | . | 33 | 55 | 47 | 50 | 46 | 40 | 9 | . | . |
A10BD11 Metformine met linagliptine | . | . | . | . | . | . | . | . | . | 7 | 73 | 140 | 171 | 187 | 192 | 217 | 270 | 270 | 293 |
A10BD15 Metformine met dapagliflozine | . | . | . | . | . | . | . | . | . | . | . | 42 | 131 | 206 | 235 | 275 | 311 | 337 | 390 |
A10BD16 Metformine met canagliflozine | . | . | . | . | . | . | . | . | . | . | . | . | 2 | 5 | 3 | 7 | 2 | . | . |
A10BD20 Metformine met empagliflozine | . | . | . | . | . | . | . | . | . | . | . | . | 2 | 70 | 253 | 360 | 386 | 400 | 446 |
A10BD23 Metformine met ertugliflozine | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 1 | 1 |
A10BF01 Acarbose | 6.695 | 5.471 | 4.420 | 3.288 | 2.634 | 2.061 | 1.599 | 1.297 | 1.139 | 984 | 1.101 | 1.469 | 1.406 | 1.425 | 1.454 | 1.401 | 1.236 | 900 | 781 |
A10BG03 Pioglitazon | 9.056 | 14.391 | 17.845 | 24.284 | 24.733 | 20.282 | 19.361 | 21.687 | 19.342 | 14.932 | 11.411 | 8.785 | 6.976 | 5.636 | 4.704 | 3.872 | 3.251 | 2.671 | 2.391 |
A10BH01 Sitagliptine | . | . | . | . | 1.290 | 5.371 | 7.469 | 12.826 | 17.590 | 23.291 | 23.606 | 22.114 | 21.445 | 21.106 | 21.738 | 24.452 | 29.401 | 31.386 | 33.246 |
A10BH02 Vildagliptine | . | . | . | . | . | 977 | 3.230 | 5.267 | 6.045 | 7.497 | 7.749 | 7.116 | 6.593 | 6.048 | 5.823 | 5.625 | 5.599 | 5.248 | 4.902 |
A10BH03 Saxagliptine | . | . | . | . | . | . | . | 1.216 | 2.441 | 2.897 | 2.609 | 2.163 | 1.797 | 1.431 | 1.280 | 1.135 | 1.064 | 962 | 846 |
A10BH05 Linagliptine | . | . | . | . | . | . | . | . | . | 2.537 | 4.495 | 5.099 | 5.582 | 6.016 | 6.528 | 7.163 | 8.581 | 9.597 | 10.280 |
A10BJ01 Exenatide | . | . | . | . | . | . | 842 | 1.269 | 1.314 | 1.910 | 1.707 | 1.518 | 1.354 | 1.168 | 989 | 870 | 746 | 586 | 477 |
A10BJ02 Liraglutide | . | . | . | . | . | . | . | 3.878 | 7.712 | 10.174 | 11.055 | 10.821 | 10.409 | 9.592 | 10.312 | 11.567 | 11.702 | 9.895 | 8.359 |
A10BJ03 Lixisenatide | . | . | . | . | . | . | . | . | . | . | . | 31 | 58 | 44 | 89 | 145 | 149 | 101 | 66 |
A10BJ05 Dulaglutide | . | . | . | . | . | . | . | . | . | . | . | . | 266 | 683 | 1.712 | 2.509 | 3.357 | 4.566 | 5.484 |
A10BJ06 Semaglutide | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 1.264 | 12.097 | 26.163 | 42.286 |
A10BK01 Dapagliflozine | . | . | . | . | . | . | . | . | . | . | 458 | 1.824 | 3.032 | 4.787 | 6.743 | 8.164 | 7.746 | 9.234 | 24.063 |
A10BK02 Canagliflozine | . | . | . | . | . | . | . | . | . | . | . | 95 | 213 | 217 | 254 | 497 | 901 | 1.279 | 1.609 |
A10BK03 Empagliflozine | . | . | . | . | . | . | . | . | . | . | . | 1 | 290 | 1.672 | 4.335 | 6.900 | 8.351 | 9.594 | 14.217 |
A10BK04 Ertugliflozine | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 17 | 13 | 15 |
A10BX02 Repaglinide | 814 | 682 | 638 | 766 | 888 | 858 | 832 | 772 | 764 | 756 | 693 | 647 | 599 | 599 | 632 | 697 | 700 | 703 | 661 |
Totaal * | 531.247 | 564.136 | 581.670 | 603.168 | 624.634 | 671.890 | 692.129 | 738.003 | 766.089 | 786.307 | 796.696 | 800.254 | 812.162 | 807.997 | 819.696 | 821.817 | 825.865 | 826.906 | 844.410 |