Top 100 van geneesmiddelen o.b.v. de vergoeding in 2018

  • Raming voor de totale Zvw-populatie
  2014 2015 2016 2017 2018
Rang
2018
ATC-code  
1 R07AX30 Ivacaftor met lumacaftor (Orkambi ®)       5.765.200 89.532.400
2 R03BB04 Tiotropium (Spiriva ®) 86.636.700 85.268.100 79.932.600 72.642.600 64.497.300
3 B01AF01 Rivaroxaban (Xarelto ®) 7.394.400 15.207.200 27.527.900 43.412.000 61.257.800
4 J06BA02 Immunoglobuline normaal intravasculair (Nanogam ®) 35.516.500 41.989.900 48.124.700 53.707.300 60.812.000
5 B01AF02 Apixaban (Eliquis ®) 2.035.500 7.835.700 17.148.000 31.311.900 46.026.100
6 R03AK08 Formoterol met beclometason (Foster ®) 26.703.100 30.917.600 36.872.600 42.551.400 45.696.400
7 A10AB05 Insuline aspart (Novorapid ®) 43.366.400 44.177.100 44.727.900 45.342.600 45.006.500
8 N02AB03 Fentanyl (Abstral ®) 27.704.400 32.710.800 35.512.900 39.918.200 44.102.600
9 A10AE04 Insuline glargine (Lantus ®) 47.859.500 51.077.700 50.254.400 46.570.200 44.073.600
10 R03AK06 Salmeterol met fluticason (Seretide ®) 91.080.600 81.326.900 65.230.400 54.105.700 40.356.100
11 N04BA02 Levodopa met decarboxylaseremmer (Madopar ®) 25.144.300 28.568.100 31.932.200 35.995.500 38.288.800
12 B01AE07 Dabigatranetexilaat (Pradaxa ®) 9.941.400 14.908.600 22.425.400 31.115.900 37.142.900
13 J05AR13 Lamivudine met abacavir en dolutegravir (Triumeq ®) 497.440 16.215.800 28.113.000 32.077.600 35.035.100
14 R03AK07 Formoterol met budesonide (Symbicort ®) 53.491.800 48.102.500 42.344.800 37.485.600 34.415.600
15 J05AR18 Emtricitabine tenofovir alafenamide elvitegravir cobicista (Genvoya ®)     8.899.200 26.089.100 33.297.700
16 C10AX13 Evolocumab (Repatha ®)     5.749.500 20.209.900 33.009.600
17 N07XX09 Dimethylfumaraat (Tecfidera ®) 2.470.700 16.075.200 20.508.000 23.228.100 32.174.400
18 L04AD02 Tacrolimus (Prograft ®) 24.963.500 26.778.400 28.406.600 29.575.200 31.476.200
19 C10AX09 Ezetimib (Ezetrol ®) 29.215.900 31.435.800 35.553.200 40.014.000 28.146.700
20 L04AA27 Fingolimod (Gilenya ®) 18.239.400 21.522.300 22.922.700 24.383.400 27.108.300
21 B03XA02 Darbepoetine alfa (Aranesp ®) 25.997.300 24.510.900 24.142.800 24.134.500 26.269.200
22 A12AX Calcium met vitamine d en/of andere middelen 24.781.900 26.488.800 25.261.000 26.395.400 26.159.000
23 A07EC02 Mesalazine (Pentasa compact ®) 21.619.500 23.013.600 24.300.600 24.310.300 24.992.600
24 H01CB02 Octreotide (Sandostatine ®) 23.178.700 24.552.000 24.447.000 23.381.300 23.438.000
25 L04AX03 Methotrexaat (Metoject pen ®) 2.763.100 13.903.600 20.741.900 22.372.900 22.313.900
26 A06AD65 Macrogol combinatiepreparaten (Moviprep ®) 23.169.100 24.869.400 25.394.500 20.809.500 21.850.400
27 M05BX04 Denosumab (Prolia ®) 14.109.400 19.012.700 21.162.000 21.170.900 21.306.800
28 H01CB03 Lanreotide (Somatuline ®) 12.440.200 15.102.000 16.761.300 18.777.100 20.785.200
29 C10AA07 Rosuvastatine (Crestor ®) 57.659.100 60.264.500 65.591.200 66.190.700 20.208.000
30 C10AX14 Alirocumab (Praluent ®)     1.933.100 9.789.700 20.028.800
31 A11CC05 Colecalciferol (Divisun ®) 15.731.200 22.794.100 19.713.400 17.213.300 19.022.100
32 C02KX04 Macitentan (Opsumit ®) 2.475.300 7.469.900 12.530.200 15.309.000 18.946.000
33 A09AA02 Multi-enzymen (lipase protease enz) (Creon ®) 14.932.800 15.975.500 16.827.800 17.931.600 18.885.500
34 A10AE06 Insuline degludec (Tresiba ®) 27.781 901.090 7.189.100 13.304.900 18.564.000
35 S01XA20 Kunsttranen en andere indifferente preparaten (Vidisic ®) 13.472.800 14.074.700 15.101.200 16.547.000 18.256.800
36 C08CA12 Barnidipine (Cyress ®) 13.250.100 14.377.600 15.717.100 16.927.500 17.864.500
37 A10AD05 Insuline aspart (Novomix 30 ®) 26.214.500 24.972.300 23.481.800 20.541.300 17.175.100
38 L03AB07 Interferon beta 1a (Avonex ®) 39.781.200 30.934.500 25.303.700 20.277.200 17.090.200
39 B01AC24 Ticagrelor (Brilique ®) 11.695.900 14.844.600 16.552.900 16.633.600 16.696.300
40 L03AX13 Glatirameer (Copaxone ®) 19.422.800 18.548.800 19.466.200 17.143.900 16.585.900
41 C10BA02 Simvastatine met ezetimib (Inegy ®) 21.276.800 20.326.300 19.957.700 18.765.400 16.263.600
42 L03AA13 Pegfilgrastim (Neulasta ®) 29.500.500 23.793.500 17.682.400 14.646.000 16.180.400
43 L02AE02 Leuproreline (Lucrin pds ®) 14.339.600 14.299.900 14.602.400 15.245.300 15.815.600
44 J05AP55 Sofosbuvir met velpatasvir (Epclusa ®)       11.148.200 14.595.600
45 J05AX12 Dolutegravir (Tivicay ®) 819.700 6.356.400 10.339.000 12.187.500 14.253.800
46 N06BA04 Methylfenidaat (Concerta ®) 12.242.300 12.995.700 13.146.400 13.399.000 14.176.600
47 H01AX01 Pegvisomant (Somavert ®) 12.629.700 13.493.500 13.276.000 13.775.100 13.858.600
48 A02BC01 Omeprazol (Losec mups ®) 14.297.600 14.415.500 13.772.700 13.897.800 13.827.500
49 A10BJ02 Liraglutide (Victoza ®) 12.931.600 12.654.000 12.055.400 11.941.000 13.592.800
50 S01ED51 Timolol combinatiepreparaten (Duotrav ®) 11.326.600 12.163.300 13.033.900 13.293.500 12.944.400
51 R03BA05 Fluticason (Flixotide ®) 16.086.400 15.743.800 15.273.800 14.282.800 12.922.100
52 L04AA31 Teriflunomide (Aubagio ®) 1.019.100 4.810.200 8.508.200 10.978.200 12.734.400
53 C07AB02 Metoprolol (Selokeen ®) 13.054.600 13.084.800 12.069.900 12.069.400 12.600.600
54 G04BD08 Solifenacine (Vesicare ®) 13.397.300 13.283.900 13.485.900 12.889.000 12.483.500
55 C01DA14 Isosorbidemononitraat (Mono-cedocard ®) 13.689.800 13.503.600 13.265.800 12.885.900 12.442.000
56 H05BX01 Cinacalcet (Mimpara ®) 10.181.800 11.203.000 12.293.800 12.419.800 12.427.700
57 B01AB06 Nadroparine (Fraxiparine ®) 14.891.900 15.193.500 15.003.200 13.662.100 12.344.000
58 A02BC02 Pantoprazol (Pantozol ®) 6.173.600 7.055.800 6.195.000 6.522.700 12.331.700
59 A10AE05 Insuline detemir (Levemir ®) 21.842.800 21.269.800 17.952.900 14.745.500 12.280.000
60 L02AE03 Gosereline (Zoladex ®) 11.517.000 11.075.500 11.532.300 11.790.800 12.153.100
61 N02CC01 Sumatriptan (Imigran ®) 14.149.700 13.306.500 12.960.000 11.958.200 11.970.700
62 C02KX01 Bosentan (Tracleer ®) 20.536.600 18.918.700 18.408.000 14.546.500 11.855.200
63 J06BB16 Palivizumab (Synagis ®) 14.685.000 14.057.600 12.877.100 12.788.400 11.760.900
64 J05AR17 Emtricitabine met tenofovir alafenamide (Descovy ®)     789.710 8.741.400 11.403.800
65 B01AF03 Edoxaban (Lixiana ®)   6.608 819.870 5.111.900 11.317.000
66 J06BA01 Immunoglobuline normaal extravasculair (Cuvitru ®) 6.121.700 6.946.500 7.670.700 8.360.300 10.939.100
67 L04AA06 Mycofenolzuur (Cellcept ®) 10.237.800 10.651.700 10.997.600 11.032.600 10.930.200
68 J05AX Overige antivirale middelen         10.685.700
69 N05AX13 Paliperidon (Xeplion ®) 7.505.800 7.759.100 8.628.300 9.816.100 10.616.300
70 N05AX12 Aripiprazol (Abilify ®) 19.016.600 22.442.800 16.118.400 10.797.300 10.579.000
71 R03BA08 Ciclesonide (Alvesco ®) 9.645.100 10.314.500 10.552.200 10.452.400 10.565.600
72 N02AA05 Oxycodon (Oxynorm ®) 13.687.700 11.088.100 11.854.100 10.345.100 10.533.400
73 J05AR06 Emtricitabine met tenofovir disoproxil en efavirenz (Atripla ®) 34.191.500 29.156.300 23.881.900 18.348.900 10.469.500
74 R01AD08 Fluticason (Flixonase ®) 10.800.800 9.406.100 9.586.800 9.920.700 10.364.700
75 R03AL06 Olodaterol met tiotropiumbromide (Spiolto ®)   474.520 4.872.000 8.502.300 10.352.000
76 R07AX02 Ivacaftor (Kalydeco ®)   4.888.100 9.158.500 9.043.200 10.332.200
77 R05DA04 Codeine 3.253.200 4.467.800 6.300.600 6.798.500 9.671.200
78 R03AC13 Formoterol (Atimos ®) 11.233.300 11.003.100 10.894.300 10.119.100 9.663.100
79 L01XE31 Nintedanib (Ofev ®)   219.210 5.571.800 7.702.100 9.482.000
80 A02BC05 Esomeprazol (Nexium ®) 13.225.000 11.407.400 10.908.100 9.291.800 9.455.000
81 N03AX16 Pregabaline (Lyrica ®) 41.046.200 43.696.200 31.931.100 23.810.200 9.387.300
82 B05BA10 Combinatiepreparaten (Nutriflex ®) 5.883.900 6.959.400 7.283.700 8.045.400 9.231.900
83 G04CA52 Tamsulosine met dutasteride (Combodart ®) 7.594.900 7.919.000 8.118.800 8.698.400 9.063.700
84 J05AR19 Emtricitabine met tenofovir alafenamide en rilpivirine (Odefsey ®)     324.220 5.335.900 8.864.800
85 L04AX05 Pirfenidon (Esbriet ®) 3.117.000 6.148.200 6.529.600 6.873.800 8.851.300
86 J05AR09 Emtricitabine met tenofovir elvitegravir en cobicistat (Stribild ®) 6.489.100 13.214.000 13.912.800 9.641.100 8.780.300
87 A10BA02 Metformine (Glucient ®) 8.373.300 8.357.600 8.355.500 8.488.500 8.763.900
88 C10AA05 Atorvastatine (Lipitor ®) 9.991.900 9.159.900 8.821.600 7.809.400 8.752.000
89 N06BA02 Dexamfetamine (Amfexa ®) 3.328.500 4.842.900 5.859.300 6.936.700 8.628.100
90 B01AC07 Dipyridamol (Persantin ®) 13.344.800 12.591.000 10.976.000 9.134.200 8.445.700
91 L02BA03 Fulvestrant (Faslodex ®) 4.538.500 4.020.800 5.067.600 6.864.800 8.400.100
92 B01AB04 Dalteparine (Fragmin ®) 8.868.400 9.182.800 9.423.300 9.233.300 8.326.000
93 J06BA Normaal humaan immunoglobuline 586.920 2.842.500 4.919.600 7.003.500 8.215.600
94 R03AC02 Salbutamol (Ventolin ®) 8.863.700 8.607.400 8.381.500 7.920.100 8.170.800
95 V01AA Allergeenextracten 11.873.900 6.342.600 6.467.900 6.143.500 8.156.900
96 B01AC06 Acetylsalicylzuur (Aspirine protect ®) 8.593.100 8.717.200 8.509.200 9.068.900 8.075.700
97 A10BH01 Sitagliptine (Januvia ®) 8.383.600 8.118.100 7.859.000 7.499.700 8.059.100
98 D05BX51 Fumaarzuurderivaten combinatiepreparaten (Skilarence ®) 5.254.700 6.408.900 6.921.300 7.037.700 7.898.800
99 A05AA02 Ursodeoxycholzuur (Ursochol ®) 7.077.200 7.252.000 7.519.400 7.621.900 7.846.500
100 N02AA01 Morfine (Oramorph ®) 5.277.700 6.494.000 6.676.500 7.077.000 7.790.700