Top 100 van geneesmiddelen o.b.v. de vergoeding in 2021
- Raming voor de totale Zvw-populatie
| 2017 | 2018 | 2019 | 2020 | 2021 | ||
|---|---|---|---|---|---|---|
| Rang 2021 |
ATC-code | |||||
| 1 | B01AF01 Rivaroxaban (Xarelto ®) | 43.405.900 | 61.255.400 | 79.581.600 | 91.620.800 | 99.319.500 |
| 2 | B01AF02 Apixaban (Eliquis ®) | 31.311.200 | 46.041.300 | 61.322.400 | 76.708.900 | 92.040.500 |
| 3 | J06BA02 Immunoglobuline normaal intravasculair (Nanogam ®) | 53.696.200 | 61.820.000 | 67.401.800 | 72.223.300 | 74.051.500 |
| 4 | C10AX13 Evolocumab (Repatha ®) | 20.213.900 | 33.398.200 | 39.992.200 | 48.228.100 | 55.452.200 |
| 5 | L04AX07 Dimethylfumaraat (Tecfidera ®) | 26.212.400 | 36.651.100 | 48.682.500 | 51.172.100 | 51.623.100 |
| 6 | R03AK08 Formoterol met beclometason (Foster ®) | 42.546.900 | 45.571.400 | 48.169.200 | 52.564.200 | 49.759.900 |
| 7 | C10AX14 Alirocumab (Praluent ®) | 9.788.000 | 20.154.800 | 30.221.700 | 41.013.500 | 47.595.400 |
| 8 | N02AB03 Fentanyl (Abstral ®) | 39.916.400 | 44.016.400 | 46.309.800 | 48.549.800 | 46.447.000 |
| 9 | N04BA02 Levodopa met decarboxylaseremmer (Sinemet ®) | 35.995.000 | 38.667.100 | 43.358.300 | 44.783.300 | 41.655.400 |
| 10 | R03BB04 Tiotropium (Spiriva ®) | 72.637.400 | 64.080.400 | 59.103.400 | 55.157.900 | 39.004.800 |
| 11 | A10AB05 Insuline aspart (Novorapid ®) | 45.338.800 | 44.937.800 | 44.948.900 | 43.825.600 | 38.614.900 |
| 12 | R07AX30 Ivacaftor met lumacaftor (Orkambi ®) | 7.118.000 | 89.989.900 | 67.653.000 | 42.097.600 | 37.701.300 |
| 13 | R07AX02 Ivacaftor (Kalydeco ®) | 9.238.200 | 10.484.000 | 22.203.000 | 39.515.800 | 37.333.400 |
| 14 | A10BJ06 Semaglutide (Ozempic ®) | . | 380.020 | 9.289.300 | 24.153.100 | 36.065.100 |
| 15 | A10AE04 Insuline glargine (Abasaglar ®) | 46.567.900 | 43.865.900 | 41.164.100 | 39.586.600 | 33.870.300 |
| 16 | B01AE07 Dabigatranetexilaat (Pradaxa ®) | 31.113.700 | 37.162.600 | 39.981.700 | 36.107.300 | 30.657.500 |
| 17 | C09DX04 Valsartan met sacubitril (Entresto ®) | 2.779.800 | 6.565.300 | 12.007.500 | 19.356.600 | 29.661.000 |
| 18 | J05AR20 Emtricitabine met tenofoviralafenamide en bictegravir (Biktarvy ®) | . | 866.360 | 15.884.800 | 24.907.900 | 28.354.500 |
| 19 | L04AD02 Tacrolimus (Prograft ®) | 29.571.600 | 31.591.500 | 33.212.600 | 33.051.800 | 27.787.300 |
| 20 | B01AF03 Edoxaban (Lixiana ®) | 5.111.300 | 11.379.000 | 17.799.400 | 23.596.200 | 27.326.300 |
| 21 | R07AX31 Ivacaftor met tezacaftor (Symkevi ®) | . | . | 12.106.600 | 31.613.500 | 27.141.400 |
| 22 | A07EC02 Mesalazine (Pentasa compact ®) | 24.306.500 | 24.980.800 | 24.734.900 | 26.547.000 | 26.739.500 |
| 23 | B03XA02 Darbepoetine alfa (Aranesp ®) | 24.154.600 | 26.005.200 | 28.509.400 | 29.549.500 | 26.654.000 |
| 24 | A11CC05 Colecalciferol (D-cura ®) | 17.306.800 | 19.193.200 | 27.810.900 | 30.935.900 | 26.328.000 |
| 25 | L04AA27 Fingolimod (Gilenya ®) | 24.380.400 | 27.140.800 | 27.466.100 | 25.303.800 | 25.242.300 |
| 26 | R03AK07 Formoterol met budesonide (Symbicort ®) | 37.898.300 | 34.447.700 | 30.946.200 | 30.121.600 | 25.056.500 |
| 27 | A06AD65 Macrogol combinatiepreparaten (Pleinvue ®) | 20.840.000 | 21.769.600 | 22.959.800 | 23.442.100 | 24.068.600 |
| 28 | A09AA02 Multi-enzymen (lipase protease enz) (Creon ®) | 17.934.200 | 18.891.800 | 21.110.300 | 22.960.700 | 23.967.000 |
| 29 | J05AR18 Emtricitabine tenofovir alafenamide elvitegravir cobicista (Genvoya ®) | 26.084.400 | 33.761.900 | 31.923.000 | 27.966.100 | 23.644.000 |
| 30 | A12AX Calcium met vitamine d en/of andere middelen | 26.397.200 | 26.327.200 | 27.276.200 | 28.743.700 | 23.179.300 |
| 31 | S01XA20 Kunsttranen en andere indifferente preparaten (Vidisic ®) | 17.081.800 | 18.810.600 | 20.101.200 | 21.082.100 | 22.907.700 |
| 32 | H01CB03 Lanreotide (Somatuline ®) | 18.775.100 | 20.823.000 | 23.342.800 | 25.068.200 | 22.373.200 |
| 33 | J05AR13 Lamivudine met abacavir en dolutegravir (Triumeq ®) | 32.075.500 | 35.245.200 | 32.866.400 | 27.020.500 | 20.891.900 |
| 34 | C02KX04 Macitentan (Opsumit ®) | 15.307.500 | 18.914.600 | 20.323.200 | 22.101.100 | 20.459.400 |
| 35 | L04AX03 Methotrexaat (Injexate ®) | 22.371.000 | 22.301.000 | 21.886.300 | 21.861.100 | 20.222.200 |
| 36 | N06BA04 Methylfenidaat (Medikinet ®) | 13.407.800 | 14.428.000 | 19.267.200 | 18.998.700 | 19.822.700 |
| 37 | A10AE06 Insuline degludec (Tresiba ®) | 13.313.200 | 18.504.900 | 19.282.400 | 19.547.700 | 19.733.600 |
| 38 | C07AB02 Metoprolol (Selokeen ®) | 12.123.200 | 12.574.900 | 13.098.900 | 14.287.300 | 19.725.900 |
| 39 | C08CA12 Barnidipine (Cyress ®) | 16.926.900 | 17.858.600 | 18.026.600 | 18.686.600 | 19.466.500 |
| 40 | R03AK06 Salmeterol met fluticason (Seretide ®) | 54.101.100 | 40.153.000 | 32.563.200 | 29.710.000 | 18.726.800 |
| 41 | M05BX04 Denosumab (Prolia ®) | 21.183.100 | 21.348.600 | 22.381.700 | 20.312.600 | 18.172.700 |
| 42 | L01EX09 Nintedanib (Ofev ®) | 7.704.100 | 9.377.100 | 10.458.000 | 11.985.900 | 17.350.900 |
| 43 | N06BA02 Dexamfetamine (Tentin ®) | 6.935.700 | 8.498.900 | 12.091.300 | 16.316.100 | 16.773.900 |
| 44 | J06BA01 Immunoglobuline normaal extravasculair (Cuvitru ®) | 8.357.700 | 10.940.400 | 13.945.300 | 15.830.500 | 16.589.900 |
| 45 | L04AA31 Teriflunomide (Aubagio ®) | 10.976.800 | 12.681.800 | 14.052.400 | 15.093.400 | 15.718.800 |
| 46 | B01AC24 Ticagrelor (Brilique ®) | 16.633.600 | 16.607.100 | 17.245.000 | 16.772.500 | 15.660.300 |
| 47 | A02BC02 Pantoprazol (Pantozol ®) | 6.522.300 | 12.131.600 | 10.617.500 | 12.564.000 | 15.536.700 |
| 48 | R03AL09 Formoterol met glycopyrroniumbromide en beclometason (Trimbow ®) | 22.055 | 2.537.900 | 8.110.200 | 12.606.400 | 15.304.900 |
| 49 | H01CB02 Octreotide (Sandostatine ®) | 23.379.500 | 23.427.100 | 22.726.900 | 21.123.500 | 15.067.200 |
| 50 | J05AJ03 Dolutegravir (Tivicay ®) | 12.185.000 | 14.475.800 | 15.927.000 | 14.908.100 | 13.821.100 |
| 51 | N02CC01 Sumatriptan (Imigran ®) | 11.977.700 | 12.144.800 | 12.621.800 | 12.125.100 | 13.490.400 |
| 52 | A02BC01 Omeprazol (Losec mups ®) | 13.937.700 | 13.907.500 | 13.322.600 | 14.888.300 | 13.445.800 |
| 53 | B02BX05 Eltrombopag (Revolade ®) | 5.998.100 | 7.462.900 | 9.773.600 | 11.893.200 | 13.220.100 |
| 54 | N05AX13 Paliperidon (Xeplion ®) | 9.813.800 | 10.571.000 | 11.773.300 | 12.625.400 | 12.661.300 |
| 55 | L02AE03 Gosereline (Zoladex ®) | 11.797.300 | 12.183.900 | 13.141.800 | 13.352.700 | 12.648.300 |
| 56 | S01ED51 Timolol combinatiepreparaten (Ganfort ®) | 13.308.000 | 12.957.900 | 13.350.700 | 13.123.900 | 12.554.500 |
| 57 | L03AA13 Pegfilgrastim (Pelgraz ®) | 14.659.700 | 15.907.200 | 15.476.800 | 14.294.300 | 12.294.400 |
| 58 | L02AE02 Leuproreline (Lucrin pds ®) | 15.245.600 | 15.461.200 | 15.829.700 | 15.527.300 | 12.105.900 |
| 59 | A10BA02 Metformine (Glucient ®) | 8.526.600 | 8.700.100 | 9.077.400 | 10.345.300 | 12.029.400 |
| 60 | H01AX01 Pegvisomant (Somavert ®) | 13.771.100 | 13.944.500 | 14.141.900 | 12.973.000 | 11.953.200 |
| 61 | R03AL06 Olodaterol met tiotropiumbromide (Spiolto ®) | 8.501.800 | 10.306.900 | 12.178.800 | 13.188.500 | 11.750.300 |
| 62 | J05AR25 Lamivudine met dolutegravir (Dovato ®) | . | . | 498.670 | 6.201.100 | 11.708.300 |
| 63 | J06BA Normaal humaan immunoglobuline | 7.000.900 | 8.342.400 | 10.638.500 | 12.554.600 | 11.690.900 |
| 64 | N05AX12 Aripiprazol (Abilify maintena ®) | 10.797.200 | 10.436.100 | 11.191.100 | 11.732.300 | 11.669.700 |
| 65 | H02AB09 Hydrocortison (Acecort ®) | 4.435.100 | 4.971.900 | 5.918.800 | 8.128.700 | 11.237.800 |
| 66 | C01DA14 Isosorbidemononitraat (Mono-cedocard ®) | 12.885.300 | 12.386.900 | 11.743.500 | 11.566.300 | 11.056.600 |
| 67 | B02BX04 Romiplostim (Nplate ®) | 5.869.500 | 6.984.800 | 8.022.900 | 9.468.300 | 10.952.600 |
| 68 | J05AR22 Emtricitabine tenofoviralafenamide darunavir cobicistat (Symtuza ®) | 70.648 | 5.658.900 | 10.280.400 | 11.410.700 | 10.936.500 |
| 69 | L03AX13 Glatirameer (Copaxone ®) | 17.140.800 | 16.581.500 | 12.882.300 | 11.891.400 | 10.772.500 |
| 70 | D02AX Overige emollientia en protectiva | 5.224.500 | 6.745.800 | 8.457.700 | 9.575.900 | 10.672.900 |
| 71 | R03BA05 Fluticason (Flixotide ®) | 14.279.600 | 12.909.300 | 11.859.700 | 11.706.600 | 10.468.500 |
| 72 | A10BH01 Sitagliptine (Januvia ®) | 7.499.100 | 8.041.000 | 9.659.400 | 10.544.600 | 10.395.400 |
| 73 | L04AX05 Pirfenidon (Esbriet ®) | 6.872.600 | 8.824.600 | 10.306.500 | 10.668.100 | 10.071.200 |
| 74 | R01AD08 Fluticason (Flixonase ®) | 9.939.600 | 10.403.000 | 10.338.100 | 10.871.800 | 9.868.100 |
| 75 | C10AA05 Atorvastatine (Lipitor ®) | 7.825.900 | 8.683.200 | 9.038.000 | 10.125.800 | 9.822.300 |
| 76 | A10AD05 Insuline aspart (Novomix 30 ®) | 20.541.100 | 17.107.700 | 14.760.100 | 12.602.100 | 9.818.300 |
| 77 | V01AA02 Graspollenallergeen (Grazax ®) | 4.124.400 | 4.554.900 | 5.836.800 | 7.953.100 | 9.802.300 |
| 78 | R03BA08 Ciclesonide (Alvesco ®) | 10.450.800 | 10.559.100 | 10.448.500 | 11.198.100 | 9.676.000 |
| 79 | L04AA06 Mycofenolzuur (Cellcept ®) | 11.030.400 | 10.950.600 | 11.741.000 | 11.758.700 | 9.552.200 |
| 80 | A10BJ02 Liraglutide (Victoza ®) | 12.166.300 | 13.666.600 | 13.784.700 | 11.632.600 | 9.263.200 |
| 81 | J06BB16 Palivizumab (Synagis ®) | 12.785.800 | 11.702.600 | 9.783.000 | 9.114.300 | 9.147.800 |
| 82 | C10AA07 Rosuvastatine (Crestor ®) | 66.181.700 | 20.251.000 | 9.634.100 | 9.921.900 | 9.038.300 |
| 83 | N05AH04 Quetiapine (Seroquel ®) | 5.557.200 | 6.695.200 | 8.144.500 | 8.354.700 | 8.990.400 |
| 84 | J05AR17 Emtricitabine met tenofovir alafenamide (Descovy ®) | 8.739.900 | 11.399.900 | 10.948.600 | 9.927.000 | 8.982.700 |
| 85 | L03AB07 Interferon beta 1a (Avonex ®) | 20.274.400 | 17.219.200 | 14.600.700 | 12.207.900 | 8.875.800 |
| 86 | R03AC02 Salbutamol (Ventolin ®) | 7.922.100 | 8.138.100 | 8.809.400 | 9.488.900 | 8.872.000 |
| 87 | N02AA01 Morfine (Oramorph ®) | 7.076.600 | 7.699.800 | 7.686.100 | 8.608.000 | 8.831.300 |
| 88 | A10BB09 Gliclazide (Diamicron ®) | 4.250.400 | 5.425.000 | 6.397.300 | 6.694.300 | 8.657.000 |
| 89 | D07AB09 Triamcinolon | 7.036.200 | 5.879.300 | 6.585.900 | 7.026.900 | 8.636.500 |
| 90 | B01AB06 Nadroparine (Fraxiparine ®) | 13.664.500 | 12.310.700 | 11.347.600 | 9.356.500 | 8.489.600 |
| 91 | B01AC27 Selexipag (Uptravi ®) | 2.469.700 | 4.102.000 | 7.971.700 | 8.376.800 | 8.487.200 |
| 92 | N06BA12 Lisdexamfetamine (Elvanse ®) | . | . | 404.250 | 5.203.300 | 8.406.500 |
| 93 | A02BC05 Esomeprazol (Nexium ®) | 9.419.600 | 9.523.300 | 9.217.100 | 9.747.300 | 8.333.300 |
| 94 | L01BB03 Tioguanine (Thiosix ®) | 4.604.600 | 6.230.300 | 7.273.600 | 7.905.400 | 8.324.400 |
| 95 | R03AC13 Formoterol (Atimos ®) | 10.117.800 | 9.645.300 | 9.153.100 | 8.675.200 | 8.252.900 |
| 96 | R03AK10 Vilanterol met fluticasonfuroaat (Relvar ellipta ®) | 3.409.800 | 4.172.400 | 4.602.800 | 4.849.100 | 8.189.200 |
| 97 | R05DA04 Codeine | 6.797.700 | 9.860.100 | 12.096.800 | 9.135.200 | 8.155.400 |
| 98 | H03AA01 Levothyroxine (Euthyrox ®) | 7.891.400 | 7.737.500 | 8.036.700 | 8.224.800 | 8.150.300 |
| 99 | D05AX52 Calcipotriol combinatiepreparaten (Dovobet ®) | 7.162.100 | 7.535.400 | 8.159.000 | 8.596.500 | 7.876.600 |
| 100 | L02BA03 Fulvestrant (Faslodex ®) | 6.868.200 | 8.474.600 | 9.012.600 | 9.145.600 | 7.648.000 |