Top 100 van geneesmiddelen o.b.v. de vergoeding in 2022
- Raming voor de totale Zvw-populatie
| 2018 | 2019 | 2020 | 2021 | 2022 | ||
|---|---|---|---|---|---|---|
| Rang 2022 |
ATC-code | |||||
| 1 | R07AX32 Ivacaftor met tezacaftor en elexacaftor (Kaftrio ®) | . | . | . | . | 117.093.800 |
| 2 | B01AF02 Apixaban (Eliquis ®) | 46.041.300 | 61.322.600 | 76.708.900 | 93.343.000 | 113.391.300 |
| 3 | B01AF01 Rivaroxaban (Xarelto ®) | 61.255.400 | 79.582.800 | 91.620.800 | 100.546.900 | 111.884.900 |
| 4 | J06BA02 Immunoglobuline normaal intravasculair (Nanogam ®) | 61.820.000 | 67.401.800 | 72.223.300 | 74.482.700 | 84.186.800 |
| 5 | R07AX02 Ivacaftor (Kalydeco ®) | 10.484.000 | 22.203.000 | 39.515.800 | 37.385.800 | 75.053.000 |
| 6 | C10AX13 Evolocumab (Repatha ®) | 33.398.200 | 39.992.200 | 48.228.100 | 55.537.900 | 66.453.700 |
| 7 | C10AX14 Alirocumab (Praluent ®) | 20.154.800 | 30.221.700 | 41.013.500 | 47.665.500 | 58.353.900 |
| 8 | A10BJ06 Semaglutide (Ozempic ®) | 380.020 | 9.289.800 | 24.153.100 | 36.169.000 | 54.934.500 |
| 9 | R03AK08 Formoterol met beclometason (Foster ®) | 45.571.400 | 48.169.200 | 52.564.200 | 49.842.500 | 54.470.000 |
| 10 | L04AX07 Dimethylfumaraat (Skilarence ®) | 36.651.100 | 48.706.500 | 51.172.100 | 51.535.400 | 52.610.000 |
| 11 | N02AB03 Fentanyl (Instanyl ®) | 44.016.400 | 46.310.000 | 48.549.800 | 46.531.600 | 49.534.600 |
| 12 | C09DX04 Valsartan met sacubitril (Entresto ®) | 6.565.300 | 12.007.500 | 19.356.600 | 29.710.400 | 49.495.000 |
| 13 | N04BA02 Levodopa met decarboxylaseremmer (Sinemet ®) | 38.667.100 | 43.358.700 | 44.783.300 | 41.651.300 | 43.634.300 |
| 14 | A10AB05 Insuline aspart (Novorapid ®) | 44.937.800 | 44.948.900 | 43.825.600 | 38.845.600 | 40.162.500 |
| 15 | A10AE04 Insuline glargine (Abasaglar ®) | 43.865.900 | 41.164.100 | 39.586.600 | 34.040.400 | 34.709.400 |
| 16 | J05AR20 Emtricitabine met tenofoviralafenamide en bictegravir (Biktarvy ®) | 866.360 | 15.884.800 | 24.907.900 | 28.509.200 | 34.595.400 |
| 17 | R03BB04 Tiotropium (Spiriva ®) | 64.080.400 | 59.435.700 | 55.157.900 | 39.116.300 | 33.616.000 |
| 18 | B01AF03 Edoxaban (Lixiana ®) | 11.379.000 | 17.800.500 | 23.596.200 | 27.756.200 | 32.172.500 |
| 19 | B01AE07 Dabigatranetexilaat (Pradaxa ®) | 37.162.600 | 39.982.000 | 36.107.300 | 30.951.300 | 30.745.200 |
| 20 | L04AD02 Tacrolimus (Prograft ®) | 31.591.500 | 33.212.600 | 33.051.800 | 27.851.900 | 28.974.700 |
| 21 | A07EC02 Mesalazine (Pentasa compact ®) | 24.980.800 | 24.734.900 | 26.547.000 | 26.748.700 | 28.276.800 |
| 22 | A11CC05 Colecalciferol (D-cura ®) | 19.193.200 | 28.054.200 | 30.935.900 | 26.386.700 | 27.036.900 |
| 23 | N07XX08 Tafamidis (Vyndaqel ®) | 2.514.700 | 3.486.900 | 3.879.500 | 3.545.500 | 26.855.300 |
| 24 | A09AA02 Multi-enzymen (lipase protease enz) (Creon ®) | 18.891.800 | 21.110.300 | 22.960.700 | 23.995.300 | 26.770.100 |
| 25 | A12AX Calcium met vitamine d en/of andere middelen | 26.327.200 | 27.870.800 | 28.743.700 | 23.253.600 | 25.414.400 |
| 26 | S01XA20 Kunsttranen en andere indifferente preparaten (Hylan ®) | 18.810.600 | 20.668.500 | 21.082.100 | 22.951.400 | 24.965.400 |
| 27 | A06AD65 Macrogol combinatiepreparaten (Pleinvue ®) | 21.769.600 | 23.062.200 | 23.442.100 | 24.104.900 | 24.266.400 |
| 28 | R03AK07 Formoterol met budesonide (Symbicort ®) | 34.447.700 | 30.946.200 | 30.121.600 | 25.089.600 | 24.065.900 |
| 29 | L04AA27 Fingolimod (Gilenya ®) | 27.140.800 | 27.466.100 | 25.303.800 | 25.289.700 | 23.853.100 |
| 30 | C02KX04 Macitentan (Opsumit ®) | 18.914.600 | 20.323.200 | 22.101.100 | 20.538.500 | 23.724.800 |
| 31 | L01EX09 Nintedanib (Ofev ®) | 9.377.100 | 10.458.000 | 11.985.900 | 17.404.500 | 23.088.000 |
| 32 | N06BA04 Methylfenidaat (Medikinet ®) | 14.428.000 | 19.333.500 | 18.998.700 | 19.704.600 | 22.283.100 |
| 33 | H01CB03 Lanreotide (Somatuline ®) | 20.823.000 | 23.342.800 | 25.068.200 | 22.420.300 | 21.726.300 |
| 34 | A10AE06 Insuline degludec (Tresiba ®) | 18.504.900 | 19.282.400 | 19.547.700 | 19.769.600 | 21.655.600 |
| 35 | J05AR18 Emtricitabine tenofovir alafenamide elvitegravir cobicista (Genvoya ®) | 33.761.900 | 31.923.000 | 27.966.100 | 23.652.300 | 21.655.000 |
| 36 | C07AB02 Metoprolol (Selokeen ®) | 12.574.900 | 13.149.400 | 14.287.300 | 19.741.700 | 21.167.100 |
| 37 | A10BK01 Dapagliflozine (Forxiga ®) | 2.952.400 | 2.900.400 | 3.344.500 | 5.403.600 | 21.032.600 |
| 38 | R03AL09 Formoterol met glycopyrroniumbromide en beclometason (Trimbow ®) | 2.537.900 | 8.110.200 | 12.606.400 | 15.329.800 | 20.880.300 |
| 39 | C08CA12 Barnidipine (Cyress ®) | 17.858.600 | 18.026.600 | 18.686.600 | 19.483.700 | 20.453.900 |
| 40 | N06BA02 Dexamfetamine (Tentin ®) | 8.498.900 | 12.102.100 | 16.316.100 | 16.744.600 | 20.340.200 |
| 41 | M05BX04 Denosumab (Prolia ®) | 21.348.600 | 22.381.700 | 20.312.600 | 18.234.000 | 19.427.100 |
| 42 | L04AX03 Methotrexaat (Injexate ®) | 22.301.000 | 21.885.800 | 21.861.100 | 20.240.900 | 19.076.500 |
| 43 | J05AR13 Lamivudine met abacavir en dolutegravir (Triumeq ®) | 35.245.200 | 33.019.900 | 27.020.500 | 20.926.900 | 18.958.000 |
| 44 | J06BA01 Immunoglobuline normaal extravasculair (Cuvitru ®) | 10.940.400 | 13.945.300 | 15.830.500 | 16.638.900 | 18.223.000 |
| 45 | A02BC02 Pantoprazol (Pantozol ®) | 12.131.600 | 10.660.000 | 12.564.000 | 15.554.500 | 17.808.200 |
| 46 | A10BJ02 Liraglutide (Victoza ®) | 13.666.600 | 13.785.300 | 11.632.600 | 9.275.700 | 17.689.100 |
| 47 | J05AR25 Lamivudine met dolutegravir (Dovato ®) | . | 498.670 | 6.201.100 | 11.691.500 | 17.124.100 |
| 48 | R03AK06 Salmeterol met fluticason (Seretide ®) | 40.153.000 | 32.766.700 | 29.710.000 | 18.776.200 | 16.973.700 |
| 49 | B02BX05 Eltrombopag (Revolade ®) | 7.462.900 | 9.773.600 | 11.893.200 | 13.246.000 | 16.664.200 |
| 50 | B01AC24 Ticagrelor (Brilique ®) | 16.607.100 | 17.245.000 | 16.772.500 | 15.665.200 | 16.287.300 |
| 51 | L04AA31 Teriflunomide (Aubagio ®) | 12.681.800 | 14.052.400 | 15.093.400 | 15.710.200 | 16.279.900 |
| 52 | R07AX30 Ivacaftor met lumacaftor (Orkambi ®) | 89.989.900 | 67.653.000 | 42.097.600 | 37.638.900 | 15.526.100 |
| 53 | N02CC01 Sumatriptan (Imigran ®) | 12.144.800 | 12.669.200 | 12.125.100 | 13.514.900 | 15.227.800 |
| 54 | J05AJ03 Dolutegravir (Tivicay ®) | 14.475.800 | 15.927.000 | 14.908.100 | 13.843.600 | 14.960.200 |
| 55 | H01CB02 Octreotide (Sandostatine ®) | 23.427.100 | 22.726.900 | 21.123.500 | 15.103.300 | 14.470.500 |
| 56 | D02AX Overige emollientia en protectiva | 6.745.800 | 8.490.400 | 9.575.900 | 10.763.600 | 14.286.000 |
| 57 | S01ED51 Timolol combinatiepreparaten (Ganfort ®) | 12.957.900 | 13.388.100 | 13.123.900 | 12.568.400 | 13.982.200 |
| 58 | N05AX12 Aripiprazol (Abilify maintena ®) | 10.436.100 | 11.191.100 | 11.732.300 | 11.690.900 | 13.966.800 |
| 59 | R01AD08 Fluticason (Flixonase ®) | 10.403.000 | 10.340.000 | 10.871.800 | 9.878.700 | 13.389.600 |
| 60 | N05AX13 Paliperidon (Xeplion ®) | 10.571.000 | 11.772.500 | 12.625.400 | 12.704.300 | 13.354.700 |
| 61 | A02BC01 Omeprazol (Losec mups ®) | 13.907.500 | 13.560.800 | 14.888.300 | 13.461.500 | 13.230.700 |
| 62 | L02AE03 Gosereline (Zoladex ®) | 12.183.900 | 13.141.800 | 13.352.700 | 12.678.500 | 13.219.800 |
| 63 | H02AB09 Hydrocortison (Acecort ®) | 4.971.900 | 5.918.500 | 8.128.700 | 11.251.300 | 12.919.000 |
| 64 | R03AL06 Olodaterol met tiotropiumbromide (Spiolto ®) | 10.306.900 | 12.178.800 | 13.188.500 | 11.790.100 | 12.849.000 |
| 65 | J06BA Normaal humaan immunoglobuline | 8.342.400 | 10.638.500 | 12.554.600 | 11.943.300 | 12.500.000 |
| 66 | A10BK03 Empagliflozine (Jardiance ®) | 2.399.000 | 2.959.500 | 3.538.100 | 4.115.700 | 12.390.600 |
| 67 | A10BA02 Metformine (Glucient ®) | 8.700.100 | 9.134.200 | 10.345.300 | 12.048.000 | 12.289.100 |
| 68 | B02BX04 Romiplostim (Nplate ®) | 6.984.800 | 8.022.900 | 9.468.300 | 11.000.300 | 12.284.000 |
| 69 | C01DA14 Isosorbidemononitraat (Mono-cedocard ®) | 12.386.900 | 11.743.400 | 11.566.300 | 11.070.800 | 11.764.300 |
| 70 | L02AE02 Leuproreline (Lucrin pds ®) | 15.461.200 | 15.829.700 | 15.527.300 | 12.108.100 | 11.711.400 |
| 71 | H01AX01 Pegvisomant (Somavert ®) | 13.944.500 | 14.141.900 | 12.973.000 | 11.956.300 | 11.706.900 |
| 72 | J05AR22 Emtricitabine tenofoviralafenamide darunavir cobicistat (Symtuza ®) | 5.658.900 | 10.280.400 | 11.410.700 | 10.965.300 | 11.625.000 |
| 73 | N06BA12 Lisdexamfetamine (Elvanse ®) | . | 413.540 | 5.203.300 | 8.391.500 | 11.483.000 |
| 74 | L04AX05 Pirfenidon (Esbriet ®) | 8.824.600 | 10.306.500 | 10.668.100 | 10.045.200 | 11.007.500 |
| 75 | V01AA02 Graspollenallergeen (Grazax ®) | 4.554.900 | 5.836.800 | 7.953.100 | 9.789.500 | 10.939.700 |
| 76 | A10BH01 Sitagliptine (Januvia ®) | 8.041.000 | 9.659.400 | 10.544.600 | 10.431.900 | 10.629.400 |
| 77 | C10AA05 Atorvastatine (Lipitor ®) | 8.683.200 | 9.065.100 | 10.125.800 | 9.815.700 | 10.610.600 |
| 78 | R03BA08 Ciclesonide (Alvesco ®) | 10.559.100 | 10.515.200 | 11.198.100 | 9.684.600 | 10.456.700 |
| 79 | R03BA05 Fluticason (Flixotide ®) | 12.909.300 | 11.859.700 | 11.706.600 | 10.476.900 | 10.285.700 |
| 80 | L04AA40 Cladribine (Mavenclad ®) | 2.290.500 | 4.653.000 | 3.939.500 | 5.276.500 | 10.281.400 |
| 81 | C10AA07 Rosuvastatine (Crestor ®) | 20.251.000 | 9.729.000 | 9.921.900 | 9.015.900 | 10.180.300 |
| 82 | B06AC01 C1-esteraseremmer uit plasma (Cinryze ®) | 5.237.100 | 6.303.300 | 5.369.400 | 5.243.000 | 10.173.400 |
| 83 | B01AC27 Selexipag (Uptravi ®) | 4.102.000 | 7.971.700 | 8.376.800 | 8.491.500 | 10.154.600 |
| 84 | D07AB09 Triamcinolon | 5.879.300 | 6.585.900 | 7.026.900 | 8.631.300 | 9.856.500 |
| 85 | N05AH04 Quetiapine (Seroquel ®) | 6.695.200 | 8.144.800 | 8.354.700 | 8.974.400 | 9.854.900 |
| 86 | L04AA06 Mycofenolzuur (Cellcept ®) | 10.950.600 | 11.741.300 | 11.758.700 | 9.562.600 | 9.724.800 |
| 87 | R03AC02 Salbutamol (Ventolin ®) | 8.138.100 | 8.861.500 | 9.488.900 | 8.887.200 | 9.393.500 |
| 88 | L03AX13 Glatirameer (Copaxone ®) | 16.581.500 | 12.882.300 | 11.891.400 | 10.807.200 | 9.330.900 |
| 89 | A10BB09 Gliclazide (Diamicron ®) | 5.425.000 | 6.399.600 | 6.694.300 | 8.658.800 | 9.240.400 |
| 90 | J05AR17 Emtricitabine met tenofovir alafenamide (Descovy ®) | 11.399.900 | 10.948.600 | 9.927.000 | 9.001.600 | 9.186.700 |
| 91 | L01BB03 Tioguanine (Thiosix ®) | 6.230.300 | 7.274.800 | 7.905.400 | 8.335.500 | 9.173.700 |
| 92 | R05DA04 Codeine | 9.860.100 | 12.146.000 | 9.135.200 | 8.177.700 | 9.160.900 |
| 93 | N02AA01 Morfine (Oramorph ®) | 7.699.800 | 7.686.500 | 8.608.000 | 8.853.700 | 9.090.200 |
| 94 | J05AR24 Lamivudine met tenofovir disoproxil en doravirine (Delstrigo ®) | . | 247.790 | 3.649.700 | 7.052.200 | 9.088.100 |
| 95 | R03AK10 Vilanterol met fluticasonfuroaat (Relvar ellipta ®) | 4.172.400 | 4.602.800 | 4.849.100 | 8.200.000 | 8.905.100 |
| 96 | A10AD05 Insuline aspart (Novomix 30 ®) | 17.107.700 | 14.760.100 | 12.602.100 | 9.847.500 | 8.807.000 |
| 97 | N05CD08 Midazolam (Dormicum ®) | 5.183.500 | 5.787.500 | 6.510.600 | 7.566.300 | 8.778.300 |
| 98 | B01AB06 Nadroparine (Fraxiparine ®) | 12.310.700 | 11.347.800 | 9.356.500 | 8.504.000 | 8.621.200 |
| 99 | H03AA01 Levothyroxine (Euthyrox ®) | 7.737.500 | 8.060.900 | 8.224.800 | 8.156.800 | 8.504.900 |
| 100 | A02BC05 Esomeprazol (Nexium ®) | 9.523.300 | 9.345.200 | 9.747.300 | 8.335.100 | 8.482.800 |