Overzicht van geneesmiddelen per bijlage 2-voorwaarde, met de vergoeding van 2014 - 2018

  • Peilmoment 31-12-2018
  Vergoeding
  2014 2015 2016 2017 2018
Nummer
voorwaarde
ATC-code  
003 J07BF03 Poliomyelitis 3 typen geinactiveerd intact virus (Poliomyelitisvaccin ®) 442 486 297 407 467
  J07CA01 Difterie-poliomyelitis-tetanus (Dtp vaccin ®) 11.929 9.263 1.638 1.471 8.588
  J07CA02 Difterie-kinkhoest-poliomyelitis-tetanus (Boostrix ®) 2.796 2.387 6.112 11.305 53.140
004 J07BC01 Hepatitis b gezuiverd antigeen (Fendrix ®) 369.660 345.580 375.870 356.180 341.100
  J07BC02 Hepatitis a geinactiveerd intact virus (Havrix ®) 51.760 39.199 43.697 30.520 28.453
  J07BC20 Combinatiepreparaten (Twinrix ®) 39.870 40.764 40.756 24.825 34.391
005 J07AL01 Pneumokok gezuiverd polysaccharidenantigeen (Pneumovax-23 ®) 40.898 42.707 41.932 40.037 46.154
008 J05AE01 Saquinavir (Invirase ®) 244.930 159.770 114.680 93.111 62.696
  J05AE02 Indinavir (Crixivan ®) 18.490 16.306 13.213 9.257 6.647
  J05AE03 Ritonavir (Norvir ®) 1.435.600 1.270.000 1.044.400 798.570 615.020
  J05AE07 Fosamprenavir (Telzir ®) 114.630 71.292 48.070 34.815 12.653
  J05AE08 Atazanavir (Reyataz ®) 9.247.200 7.471.200 5.898.300 4.483.100 3.508.900
  J05AE09 Tipranavir 1.901        
  J05AE10 Darunavir (Prezista ®) 15.520.600 13.896.900 11.514.600 9.369.500 7.496.600
  J05AF01 Zidovudine (Retrovir ®) 76.529 54.545 47.977 43.341 33.182
  J05AF02 Didanosine (Videx ®) 131.650 86.910 72.288 38.300 648
  J05AF04 Stavudine (Zerit ®) 5.904 5.089 4.863 905  
  J05AF05 Lamivudine (Epivir ®) 1.086.700 825.310 723.910 592.750 525.760
  J05AF06 Abacavir (Ziagen ®) 677.290 644.640 653.630 585.930 507.490
  J05AF07 Tenofovirdisoproxil (Viread ®) 6.783.600 6.926.200 6.946.500 6.492.100 2.559.700
  J05AF09 Emtricitabine (Emtriva ®) 76.824 98.819 111.560 80.060 55.831
  J05AF13 Tenofoviralafenamide (Vemlidy ®)       58.458 522.440
  J05AG01 Nevirapine (Viramune ®) 8.700.300 7.061.800 6.306.600 4.919.000 2.775.700
  J05AG03 Efavirenz (Stocrin ®) 1.733.100 1.039.900 787.280 618.070 510.770
  J05AG04 Etravirine (Intelence ®) 1.198.300 1.115.500 1.052.000 856.580 712.290
  J05AG05 Rilpivirine (Edurant ®) 280.260 277.320 254.600 290.040 308.710
  J05AP05 Simeprevir (Olysio ®)   14.059.800 1.941.300 247.030 58.035
  J05AR01 Zidovudine met lamivudine (Combivir ®) 1.167.900 693.630 310.160 179.000 131.850
  J05AR02 Lamivudine met abacavir (Kivexa ®) 9.018.800 7.589.500 6.837.200 5.429.800 2.633.500
  J05AR03 Tenofovir disoproxil met emtricitabine (Truvada ®) 41.400.800 40.077.700 35.664.900 24.631.900 7.229.000
  J05AR04 Zidovudine met lamivudine en abacavir (Trizivir ®) 1.049.200 577.990 302.900 159.310 107.350
  J05AR06 Emtricitabine met tenofovir disoproxil en efavirenz (Atripla ®) 34.191.500 29.156.300 23.881.900 18.348.900 10.469.500
  J05AR08 Emtricitabine met tenofovir disoproxil en rilpivirine (Eviplera ®) 16.177.200 15.577.100 13.962.100 9.619.000 7.384.200
  J05AR10 Lopinavir met ritonavir (Kaletra ®) 3.611.600 2.511.500 1.634.100 1.068.000 700.780
  J05AR13 Lamivudine met abacavir en dolutegravir (Triumeq ®) 497.440 16.215.800 28.113.000 32.077.600 35.035.100
  J05AR14 Darunavir met cobicistat (Rezolsta ®)   1.449.600 3.409.300 4.117.000 3.735.100
  J05AR17 Emtricitabine met tenofovir alafenamide (Descovy ®)     789.710 8.741.400 11.403.800
  J05AR18 Emtricitabine tenofovir alafenamide elvitegravir cobicista (Genvoya ®)     8.899.200 26.089.100 33.297.700
  J05AR19 Emtricitabine met tenofovir alafenamide en rilpivirine (Odefsey ®)     324.220 5.335.900 8.864.800
  J05AR20 Emtricitabine met tenofoviralafenamide en bictegravir (Biktarvy ®)         851.120
  J05AR21 Dolutegravir met rilpivirine (Juluca ®)         129.110
  J05AR22 Emtricitabine tenofoviralafenamide darunavir cobicistat (Symtuza ®)       70.836 5.683.400
  J05AX07 Enfuvirtide (Fuzeon ®) 29.409 892 3.289    
  J05AX08 Raltegravir (Isentress ®) 10.534.100 8.333.800 6.668.200 5.478.400 5.378.400
  J05AX09 Maraviroc (Celsentri ®) 1.084.000 1.037.100 965.200 839.930 762.250
  J05AX12 Dolutegravir (Tivicay ®) 819.700 6.356.400 10.339.000 12.187.500 14.253.800
009 C10AA01 Simvastatine (Zocor ®) 7.782.100 7.650.100 6.231.600 7.558.600 7.155.300
  C10AA03 Pravastatine (Selektine ®) 3.159.600 3.039.100 3.063.300 2.738.500 2.480.300
  C10AA04 Fluvastatine (Lescol ®) 679.600 573.980 531.790 470.320 466.300
  C10AA05 Atorvastatine (Lipitor ®) 9.991.900 9.159.900 8.821.600 7.809.400 8.752.000
  C10AA07 Rosuvastatine (Crestor ®) 57.659.100 60.264.500 65.591.200 66.190.700 20.208.000
  C10AX09 Ezetimib (Ezetrol ®) 29.215.900 31.435.800 35.553.200 40.014.000 28.146.700
  C10BA02 Simvastatine met ezetimib (Inegy ®) 21.276.800 20.326.300 19.957.700 18.765.400 16.263.600
  C10BA05 Atorvastatine met ezetimib (Atozet ®)   242.290 891.160 1.405.800 1.244.300
011 L03AA02 Filgrastim (Zarzio ®) 2.471.000 2.549.600 2.485.200 2.308.900 2.660.000
  L03AA10 Lenograstim 45.755 43.168 29.529 56  
  L03AA13 Pegfilgrastim (Neulasta ®) 29.500.500 23.793.500 17.682.400 14.646.000 16.180.400
  L03AA14 Lipegfilgrastim (Lonquex ®) 652.200 4.937.400 6.008.900 5.880.300 7.338.300
013 A16AB02 Imiglucerase (Cerezyme ®) 8.207.900 7.307.700 6.751.500 7.008.300 7.042.000
  A16AB10 Velaglucerase alfa (Vpriv ®) 2.971.600 2.910.200 3.476.200 3.100.300 2.451.300
  A16AX10 Eliglustat (Cerdelga ®)       670.000 2.535.700
014 J07BG01 Rabies geinactiveerd intact virus (Rabiesvaccin merieux ®) 10.860 10.577 4.643 2.380 16.154
016 N06DA02 Donepezil (Navazil ®) 94.493 95.905 56.760 35.140 33.961
  N06DA04 Galantamine (Reminyl ®) 1.231.500 696.400 511.980 426.320 391.670
019 J06BB16 Palivizumab (Synagis ®) 14.685.000 14.057.600 12.877.100 12.788.400 11.760.900
020 R03DC03 Montelukast (Singulair ®) 3.211.500 1.674.200 1.576.600 1.378.500 1.070.100
021 B01AC04 Clopidogrel (Plavix ®) 2.514.300 2.790.600 3.130.200 3.733.000 4.451.800
  B01AC22 Prasugrel (Efient ®) 2.706.000 1.896.500 1.564.200 1.520.600 1.445.200
  B01AC30 Combinatiepreparaten (Asasantin ®) 2.354.500 2.166.400 1.902.300 1.557.500 1.257.900
023 N06BA07 Modafinil (Modiodal ®) 1.334.400 1.015.400 780.670 578.840 517.350
026 A10BD05 Metformine met pioglitazon (Competact ®) 88.746 80.474 71.695 59.269 45.443
  A10BG03 Pioglitazon (Actos ®) 497.660 325.860 239.200 163.270 111.720
027 B03XA01 Epoetine (Neorecormon ®) 11.574.000 10.357.400 9.335.300 8.109.400 7.499.100
  B03XA02 Darbepoetine alfa (Aranesp ®) 25.997.300 24.510.900 24.142.800 24.134.500 26.269.200
  B03XA03 Methoxypolyethyleenglycolepoetine beta (Mircera ®) 1.412.500 1.751.500 2.150.400 2.306.900 2.305.400
  L03AB03 Interferon gamma (Immukine ®) 348.290 380.840 400.470 421.350 478.460
  L03AB04 Interferon alfa 2a (Roferon-a ®) 191.010 183.740 143.000 121.940 112.070
  L03AB05 Interferon alfa 2b (Introna ®) 134.170 112.470 85.214 55.244 61.434
  L03AB07 Interferon beta 1a (Avonex ®) 39.781.200 30.934.500 25.303.700 20.277.200 17.090.200
  L03AB08 Interferon beta 1b (Betaferon ®) 6.698.400 5.446.000 4.662.100 3.609.000 2.794.800
  L03AB10 Peginterferon alfa 2b (Pegintron ®) 811.460 635.500 604.830 471.560 26.146
  L03AB11 Peginterferon alfa 2a (Pegasys ®) 2.125.800 1.614.100 1.400.400 1.684.200 2.104.500
  L03AB13 Peginterferon beta-1a (Plegridy ®)   2.918.900 6.377.800 5.587.700 5.285.400
  L03AX13 Glatirameer (Copaxone ®) 19.422.800 18.548.800 19.466.200 17.143.900 16.585.900
  L04AC01 Daclizumab (Zinbryta ®)       806.370 152.230
  N04BA02 Levodopa met decarboxylaseremmer (Madopar ®) 25.144.300 28.568.100 31.932.200 35.995.500 38.288.800
028 B01AC09 Epoprostenol (Veletri ®) 1.596.600 1.977.200 1.789.800 845.240 782.450
  B01AC11 Iloprost (Ventavis ®) 1.078.700 1.091.200 1.069.500 655.160 345.000
  B01AC21 Treprostinil (Remodulin ®) 4.619.300 4.342.000 4.215.200 4.203.400 5.178.200
  B01AC27 Selexipag (Uptravi ®)     480.330 2.465.300 4.142.100
  C02KX01 Bosentan (Tracleer ®) 20.536.600 18.918.700 18.408.000 14.546.500 11.855.200
  C02KX02 Ambrisentan (Volibris ®) 3.862.300 3.700.100 3.395.500 3.575.200 3.420.800
  C02KX04 Macitentan (Opsumit ®) 2.475.300 7.469.900 12.530.200 15.309.000 18.946.000
  C02KX05 Riociguat (Adempas ®)   656.350 1.863.000 2.564.200 3.245.000
  G04BE03 Sildenafil (Revatio ®) 5.734.000 5.991.700 5.965.700 4.257.400 2.240.300
  G04BE08 Tadalafil (Adcirca ®) 696.910 1.023.700 1.330.800 1.718.100 1.727.200
030 D11AH01 Tacrolimus (Protopic ®) 2.094.500 2.257.400 2.537.400 2.663.900 2.747.500
031 A16AX06 Miglustat (Zavesca ®) 1.606.700 1.685.100 1.422.300 1.424.500 1.712.800
034 D11AH02 Pimecrolimus (Elidel ®) 629.530 663.880 731.870 706.980 809.930
035 A06AB02 Bisacodyl 80.625 77.753 63.402 60.891 62.517
  A06AB06 Sennaglycosiden 406.090 379.160 377.600 368.290 355.820
  A06AC01 Psylliumzaad 6.106.400 5.733.500 5.305.000 5.176.900 5.147.700
  A06AC03 Sterculiagom 148.500 136.200 131.390 114.680 105.950
  A06AD11 Lactulose (Duphalac ®) 1.747.000 1.568.200 1.422.100 1.320.800 1.197.500
  A06AD15 Macrogol (Forlax ®) 4.410.900 4.530.300 4.653.600 4.720.300 4.836.800
  A06AD65 Macrogol combinatiepreparaten (Moviprep ®) 23.169.100 24.869.400 25.394.500 20.809.500 21.850.400
  A06AG10 Docusinezuur (na-zout) incl combinatiepreparaten 120.260 91.027 79.600 39.232 38.177
  A06AG11 Natriumlaurylsulfoacetaat incl combinatiepreparaten 630.880 621.380 633.720 647.950 735.950
  A07DA03 Loperamide (Boots pharmaceuticals ®) 636.040 633.700 651.070 675.130 728.500
  A12AA03 Calciumgluconaat 780 757 683 705 346
  A12AA04 Calciumcarbonaat (Calci chew ®) 2.491.200 2.323.300 2.425.900 2.229.000 2.189.500
  A12AA20 Calcium combinatiepreparaten 94.884 82.611 50.849 9.645 72
  R01AC01 Cromoglicinezuur 52.935 50.260 49.812 46.674 45.411
  R01AC03 Azelastine (Allergodil ®) 108.260 102.570 109.460 101.050 109.070
  R06AE07 Cetirizine 930.030 1.050.300 1.008.600 440.660 407.790
  R06AX13 Loratadine (Hooikoortstablet loratadine htp ®) 271.420 282.560 306.520 279.480 277.160
  R06AX26 Fexofenadine (Telfast ®) 1.569.500 1.620.900 1.636.900 1.509.700 1.615.600
  S01GX01 Cromoglicinezuur 116.240 108.370 104.030 96.383 96.931
  S01XA20 Kunsttranen en andere indifferente preparaten (Vidisic ®) 13.472.800 14.074.700 15.101.200 16.547.000 18.256.800
039 N06DX01 Memantine (Ebixa ®) 1.051.700 383.710 216.670 133.200 120.180
042 N06DA03 Rivastigmine (Exelon ®) 7.665.200 3.910.500 3.013.500 2.623.000 2.438.800
050 C01EB17 Ivabradine (Procoralan ®) 3.557.500 3.815.500 4.135.800 4.209.900 3.533.300
051 A10BD07 Metformine met sitagliptine (Janumet ®) 2.175.200 2.078.900 1.984.900 1.843.000 1.771.900
  A10BD08 Metformine met vildagliptine (Eucreas ®) 1.852.200 1.642.200 1.578.300 1.514.200 1.496.200
  A10BD10 Metformine met saxagliptine (Komboglyze ®) 16.464 16.423 16.016 13.132 10.796
  A10BD11 Metformine met linagliptine (Jentadueto ®) 38.983 53.962 59.959 63.212 73.590
  A10BH01 Sitagliptine (Januvia ®) 8.383.600 8.118.100 7.859.000 7.499.700 8.059.100
  A10BH02 Vildagliptine (Galvus ®) 2.117.600 1.881.200 1.721.100 1.598.300 1.468.500
  A10BH03 Saxagliptine (Onglyza ®) 835.570 681.340 580.850 484.440 419.800
  A10BH05 Linagliptine (Trajenta ®) 1.718.600 2.051.600 2.308.800 2.364.300 2.471.400
056 L01XX17 Topotecan (Hycamtin ®) 603.920        
058 A10BJ01 Exenatide (Bydureon ®) 693.090 1.255.600 1.130.000 997.870 870.280
  A10BJ02 Liraglutide (Victoza ®) 12.931.600 12.654.000 12.055.400 11.941.000 13.592.800
  A10BX04 Overige bloedglucoseverlagende middelen excl. insulines 759.460 55.009 25.245 374  
  A10BX07 Overige bloedglucoseverlagende middelen excl. insulines 490.310 271.120 97.713 5.089  
059 R05CB13 Deoxyribonuclease (Pulmozyme ®) 5.920.200 6.033.600 5.885.600 5.583.200 5.313.200
061 B02BX04 Romiplostim (Nplate ®) 5.065.300 4.934.000 5.465.400 5.862.900 7.078.800
064 G02BA03 Iud met progestagenen (Mirena ®) 907.770 955.200 1.274.000 1.132.300 1.320.200
  G02BB01 Vaginale ring met progestageen en oestrogeen (Nuvaring ®) 53.916 47.815 59.944 42.586 48.199
  G03AA03 Ethinylestradiol met lynestrenol 31.652 48      
  G03AA05 Ethinylestradiol met norethisteron 77.045 84.119 25.908 107  
  G03AA07 Ethinylestradiol met levonorgestrel (Microgynon ®) 1.925.200 1.706.400 1.627.700 1.734.300 1.857.300
  G03AA09 Ethinylestradiol met desogestrel (Marvelon ®) 148.750 135.990 139.060 140.210 161.010
  G03AA10 Ethinylestradiol met gestodeen (Minulet ®) 42.744 36.903 51.182 42.550 38.062
  G03AA11 Ethinylestradiol met norgestimaat (Cilest ®) 447 40 6.408 22.968 40.211
  G03AA12 Ethinylestradiol met drospirenon (Yasmin ®) 502.910 397.100 395.490 363.970 402.750
  G03AA13 Ethinylestradiol met norelgestromine (Evra ®) 9.596 9.181 10.794 10.305 13.506
  G03AA14 Estradiol met nomegestrol (Zoely ®) 56.968 54.584 55.453 51.786 56.728
  G03AB03 Ethinylestradiol met levonorgestrel (Trigynon ®) 102.280 88.017 90.305 79.426 73.841
  G03AB04 Ethinylestradiol met norethisteron 3.241 2.813 2.767 74  
  G03AB08 Estradiol met dienogest (Qlaira ®) 7.230 6.201 5.730 4.846 6.813
  G03AC06 Medroxyprogesteron (Depo-provera ®) 260.140 269.440 285.610 287.050 323.110
  G03AC08 Etonogestrel (Implanon nxt ®) 263.540 324.370 376.740 464.840 492.830
  G03AC09 Desogestrel (Cerazette ®) 28.161 30.136 35.583 37.667 44.078
  G03AD01 Levonorgestrel 4.277 2.633 -130 -118 -45
067 N06AA02 Imipramine 197.980 197.220 195.400 169.890 146.790
  N06AA04 Clomipramine 1.355.500 1.314.800 1.153.600 1.115.500 1.144.900
  N06AA09 Amitriptyline (Sarotex ®) 2.255.800 2.216.500 2.133.200 2.094.100 2.361.900
  N06AA10 Nortriptyline (Nortrilen ®) 3.241.700 3.385.700 3.546.700 3.684.300 3.873.700
  N06AA12 Doxepine (Sinequan ®) 91.225 104.220 102.310 95.050 91.763
  N06AA16 Dosulepine (Prothiaden ®) 74.077 65.482 63.605 54.097 47.608
  N06AA21 Maprotiline 74.964 77.747 71.845 64.799 60.129
  N06AB03 Fluoxetine (Prozac ®) 865.330 845.510 803.970 782.800 817.800
  N06AB04 Citalopram (Cipramil ®) 3.013.700 3.272.300 3.400.200 3.411.200 3.551.400
  N06AB05 Paroxetine (Seroxat ®) 3.605.700 3.620.700 3.794.200 4.148.300 3.753.100
  N06AB06 Sertraline (Zoloft ®) 1.682.700 1.886.000 1.902.100 2.022.300 2.010.800
  N06AB08 Fluvoxamine (Fevarin ®) 879.950 853.230 825.900 762.910 754.670
  N06AB10 Escitalopram (Lexapro ®) 10.176.600 2.750.300 1.680.100 1.320.400 1.460.900
  N06AF03 Fenelzine (Nardil ®) 46.506 52.499 77.081 82.343 107.290
  N06AF04 Tranylcypromine (Tracydal ®) 2.679.000 10.999.400 4.553.100 4.323.400 4.329.000
  N06AG02 Moclobemide (Aurorix ®) 174.720 167.010 157.280 139.090 134.780
  N06AX03 Mianserine (Tolvon ®) 94.760 88.893 83.922 58.734 39.061
  N06AX05 Trazodon (Trazolan ®) 578.770 558.300 574.800 523.650 547.560
  N06AX11 Mirtazapine (Remeron ®) 1.502.000 1.714.900 1.787.000 1.781.100 1.552.200
  N06AX12 Bupropion (Wellbutrin ®) 3.348.600 3.827.900 4.371.400 4.628.100 5.097.400
  N06AX16 Venlafaxine (Efexor ®) 3.563.400 3.652.900 3.661.200 3.445.600 3.519.200
  N06AX21 Duloxetine (Cymbalta ®) 7.590.800 7.576.900 4.567.600 3.275.000 3.025.400
  N06AX22 Agomelatine (Valdoxan ®) 1.551.400 1.302.300 1.074.600 942.960 857.470
  N06AX26 Vortioxetine (Brintellix ®) 764 283.990 639.430 824.390 1.072.100
070 B01AC24 Ticagrelor (Brilique ®) 11.695.900 14.844.600 16.552.900 16.633.600 16.696.300
071 A02BA01 Cimetidine 219.570 141.920 122.670 95.031 83.618
  A02BA02 Ranitidine (Zantac ®) 1.631.600 1.799.000 1.986.700 2.160.300 2.225.600
  A02BA03 Famotidine 234.240 197.790 182.580 173.310 256.350
  A02BA04 Nizatidine (Axid ®) 49.968 44.623 40.199 34.555 33.616
  A02BC01 Omeprazol (Losec mups ®) 14.297.600 14.415.500 13.772.700 13.897.800 13.827.500
  A02BC02 Pantoprazol (Pantozol ®) 6.173.600 7.055.800 6.195.000 6.522.700 12.331.700
  A02BC03 Lansoprazol (Prezal ®) 362.890 286.570 263.580 231.450 361.820
  A02BC04 Rabeprazol (Pariet ®) 1.422.100 1.173.100 1.019.800 862.490 750.430
  A02BC05 Esomeprazol (Nexium ®) 13.225.000 11.407.400 10.908.100 9.291.800 9.455.000
  M01AE52 Naproxen met esomeprazol (Vimovo ®) 80.070 67.774 57.082 45.552 43.939
073 N03AF03 Rufinamide (Inovelon ®) 104.650 121.160 124.860 129.440 140.960
074 L04AA10 Sirolimus (Rapamune ®) 1.529.700 1.532.400 1.520.200 1.454.900 1.439.700
  L04AA18 Everolimus (Certican ®) 2.639.000 3.143.800 4.051.000 4.252.200 4.881.400
076 L01BB04 Cladribine (Mavenclad ®)         2.464.300
  L04AA27 Fingolimod (Gilenya ®) 18.239.400 21.522.300 22.922.700 24.383.400 27.108.300
078 N07XX08 Tafamidis (Vyndaqel ®) 876.790 921.280 1.459.900 1.999.600 2.606.400
079 J05AE11 Proteaseremmers 670.250 50.940      
  J05AE12 Proteaseremmers 467.220 162.360      
  J05AP03 Boceprevir 11.284 5.191      
083 H05AA02 Teriparatide (Forsteo ®) 4.629.300 4.854.300 4.681.500 4.906.000 5.487.500
084 A07AA12 Fidaxomicine (Dificlir ®) 66.820 99.737 136.260 101.760 123.450
085 A10BJ03 Lixisenatide (Lyxumia ®) 6.685 37.597 35.703 51.653 89.000
  A10BJ05 Dulaglutide (Trulicity ®)   150.760 621.730 1.699.500 2.759.600
  A10BJ06 Semaglutide (Ozempic ®)         381.230
086 A10BD20 Metformine met empagliflozine (Synjardy ®)   227 18.103 67.895 127.990
  A10BK03 Empagliflozine (Jardiance ®) 24 42.900 457.320 1.273.100 2.377.000
087 J05AR09 Emtricitabine met tenofovir elvitegravir en cobicistat (Stribild ®) 6.489.100 13.214.000 13.912.800 9.641.100 8.780.300
088 L01BB02 Mercaptopurine (Puri-nethol ®) 3.146.100 4.680.700 5.073.900 4.641.100 4.592.000
090 L04AX05 Pirfenidon (Esbriet ®) 3.117.000 6.148.200 6.529.600 6.873.800 8.851.300
091 L04AA31 Teriflunomide (Aubagio ®) 1.019.100 4.810.200 8.508.200 10.978.200 12.734.400
  N07XX09 Dimethylfumaraat (Tecfidera ®) 2.470.700 16.075.200 20.508.000 23.228.100 32.174.400
092 L02AE02 Leuproreline (Lucrin pds ®) 14.339.600 14.299.900 14.602.400 15.245.300 15.815.600
093 A10BD15 Metformine met dapagliflozine (Xigduo ®) 7.416 43.083 68.436 90.707 97.835
  A10BD16 Metformine met canagliflozine (Vokanamet ®)   76 753 503 1.809
  A10BK01 Dapagliflozine (Forxiga ®) 239.200 913.220 1.587.000 2.279.400 2.915.700
  A10BK02 Canagliflozine (Invokana ®) 14.322 77.034 92.776 116.580 184.010
  A10BX09 Overige bloedglucoseverlagende middelen excl. insulines 235.380 9.017 3.120 405  
094 B02BX05 Eltrombopag (Revolade ®) 1.955.800 3.011.800 4.594.700 5.996.400 7.497.400
095 B01AF01 Rivaroxaban (Xarelto ®) 7.394.400 15.207.200 27.527.900 43.412.000 61.257.800
098 M04AA03 Febuxostat (Adenuric ®)   152.980 269.610 382.000 461.020
100 R07AX02 Ivacaftor (Kalydeco ®)   4.888.100 9.158.500 9.043.200 10.332.200
101 B01AE07 Dabigatranetexilaat (Pradaxa ®) 9.941.400 14.908.600 22.425.400 31.115.900 37.142.900
  B01AF02 Apixaban (Eliquis ®) 2.035.500 7.835.700 17.148.000 31.311.900 46.026.100
102 A06AX04 Linaclotide (Constella ®)   13.565 159.280 358.180 496.290
103 B01AF03 Edoxaban (Lixiana ®)   6.608 819.870 5.111.900 11.317.000
104 L01XE31 Nintedanib (Ofev ®)   219.210 5.571.800 7.702.100 9.482.000
105 L01BB03 Tioguanine (Thiosix ®) 641.570 670.520 2.920.500 4.604.400 6.248.000
106 C10AX13 Evolocumab (Repatha ®)     5.749.500 20.209.900 33.009.600
108 N06BA02 Dexamfetamine (Amfexa ®) 3.328.500 4.842.900 5.859.300 6.936.700 8.628.100
109 C09DX04 Valsartan met sacubitril (Entresto ®)     312.930 2.780.700 6.555.100
110 C10AX14 Alirocumab (Praluent ®)     1.933.100 9.789.700 20.028.800
111 A07AA11 Rifaximine (Xifaxan ®)     455.690 1.228.400 1.651.200
112 A10AE54 Insuline glargine met lixisenatide (Suliqua ®)       84.925 433.190
  A10AE56 Insuline degludec met liraglutide (Xultophy ®)       1.570.400 3.576.300
113 C03XA01 Tolvaptan (Jinarc ®)       812.510 1.870.000
114 R07AX30 Ivacaftor met lumacaftor (Orkambi ®)       5.765.200 89.532.400
115 N06BX13 Idebenon (Raxone ®)       110.590 2.032.700
116 R03DX07 Roflumilast (Daxas ®)         7.300
57a N03AE01 Clonazepam (Rivotril ®) 549.960 554.960 562.970 559.880 533.270
  N05BA02 Chloordiazepoxide 89.603 83.527 83.959 79.209 24.794
  N05BA04 Oxazepam (Seresta ®) 1.338.600 1.280.400 1.206.200 1.163.400 1.313.400
  N05BA05 Clorazepinezuur (di-k-zout) (Tranxene ®) 447.240 414.750 417.990 399.250 388.070
  N05BA06 Lorazepam (Temesta ®) 821.490 910.290 1.002.600 1.095.600 1.290.600
  N05BA08 Bromazepam 151.630 148.820 150.590 150.120 135.090
  N05BA09 Clobazam (Frisium ®) 385.790 396.940 404.230 420.380 408.910
  N05BA11 Prazepam (Reapam ®) 27.348 26.621 26.487 26.210 29.290
  N05BA12 Alprazolam (Xanax ®) 764.320 768.020 773.990 771.630 828.370
  N05CD01 Flurazepam 132.670 123.890 119.800 110.070 108.330
  N05CD02 Nitrazepam 120.560 112.180 109.890 106.480 98.779
  N05CD03 Flunitrazepam 75.092 98.674 106.980 106.860 113.930
  N05CD06 Lormetazepam 250.450 244.150 216.710 205.060 146.040
  N05CD07 Temazepam (Normison ®) 873.660 892.480 938.150 976.190 1.035.200
  N05CD08 Midazolam (Dormicum ®) 1.919.600 3.137.000 3.939.300 4.655.400 5.207.600
  N05CD09 Brotizolam (Lendormin ®) 47.471 46.194 45.700 47.889 46.686
  N05CD11 Loprazolam (Dormonoct ®) 52.903 51.637 52.596 51.295 51.474
  N05CF01 Zopiclon (Imovane ®) 410.840 426.880 462.120 484.060 452.480
  N05CF02 Zolpidem (Stilnoct ®) 306.540 347.570 368.610 389.820 394.240
57b N05BA01 Diazepam (Stesolid ®) 585.760 581.910 585.730 599.240 594.630